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Seth Ari Sim-Son Hoffman

Instructor, Medicine - Infectious Diseases
Research to benefit under-served populations.

Dr. Hoffman is a physician-scientist in Stanford's Division of Infectious Diseases & Geographic Medicine. He leads a research program developing tools to characterize and interrupt the mild and subclinical ("cryptic") transmission of pathogens that drive antimicrobial resistance or pose pandemic risk. His work, informed by over two decades of experience in molecular and computational biology and clinical investigation, is driven by a commitment to improving human and planetary health.

Dr. Hoffman is PI of an NIH K23 award (1K23AI182452-01: "Modeling the Impact of Interventions to Reduce Typhoidal Salmonella Transmission in the Indo-Pacific"), which is an add-on research effort to the Wellcome Trust-funded Revitalising Informal Settlements and their Environments (RISE) program. He is co-investigator on a Thrasher Research Fund E.W. "Al" Thrasher" Award entitled "Quantifying the True Burden of Pediatric Typhoidal Salmonella in Dhaka, Bangladesh," studying the subclinical/mild fraction of typhoidal Salmonella incidence in Dhaka, Bangladesh. He previously led the analysis of a cluster randomized controlled trial of a pediatric typhoid conjugate vaccine campaign program in Navi Mumbai, India.

He is a co-investigator on studies which aim to determine the intensity of Far-UVC light (222nm) and amount of triethylene glycol vapor required to inactivate SARS-CoV-2 virus in human-generated respiratory aerosols from outpatients positive for SARS-CoV-2. He is co-investigator on a Stanford Beckman Technology Development Seed Grant “Innovating Far-UVC LED Technologies for Scalable Pandemic Prevention" to develop novel LEDs that emit effective doses of Far-UVC (222nm) for pathogen disinfection.

Education

Postdoctoral Research Fellowship, Infectious Diseases, Stanford University School of Medicine (2024)
MS, Stanford University, Epidemiology and Clinical Research (2023)
Board Certification: American Board of Internal Medicine, Infectious Disease (2022)
Fellowship: Stanford University Infectious Disease Fellowships (2022) CA
Board Certification: American Board of Internal Medicine, Internal Medicine (2020)
Residency, Internal Medicine, University of Maryland Medical Center (2020)
MD, The Medical School for International Health (MSIH), Ben-Gurion University of the Negev Faculty of Health Sciences in collaboration with Columbia University Irving Medical Center (2017)
BA, Cornell University, Anthropology (2012)