Katie Solari work is aimed at identifying the genetic mechanisms that underlie Himalayan pikas’ ability to survive in severely hypoxic conditions. Himalayan pikas may be forced to shift their ranges due to climate change but some of these species may not have the genetic adaptions necessary to survive the hypoxia of their new higher elevation habitat. In an effort to get a full image of the suite of adaptations that enable the hypoxia tolerance seen in some pika species, Katie is assessing adaptations in mitochondrial candidate genes, considering the role of plasticity in gene expression using transcriptomics, as well as identifying new candidate genes through next-generation techniques.